Xuntian Jiang Selected Research

N-Acylsphingosine Galactosyltransferase

1/2021

Substrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor.

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Xuntian Jiang Research Topics

Disease

11	Globoid Cell Leukodystrophy (Krabbe Disease) 01/2022 - 01/2009
11	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021 - 01/2011
5	Demyelinating Diseases (Demyelinating Disease) 01/2022 - 12/2013
5	Type C Niemann-Pick Disease (Niemann Pick Disease, Type C) 10/2021 - 01/2016
4	Disease Progression 01/2022 - 09/2017
3	Tay-Sachs Disease 01/2022 - 01/2018
3	Inflammation (Inflammations) 01/2021 - 01/2020
3	Insulin Resistance 01/2020 - 09/2013
2	Lysosomal Storage Diseases (Lysosomal Storage Disease) 12/2021 - 04/2015
2	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 01/2021 - 02/2008
2	Type 2 Diabetes Mellitus (MODY) 01/2020 - 04/2015
2	Coronary Disease (Coronary Heart Disease) 01/2020 - 01/2018
2	Neuroinflammatory Diseases 04/2015 - 09/2012
1	Nervous System Diseases (Neurological Disorders) 01/2022
1	Seizures (Absence Seizure) 01/2022
1	Gliosis 01/2022
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2021
1	Heart Failure 01/2020
1	Farber Lipogranulomatosis 10/2019
1	Starvation 01/2019
1	Mucopolysaccharidosis IV (Morquio Syndrome) 01/2019
1	Proteinuria 01/2018
1	Squamous Cell Carcinoma of Head and Neck 01/2018
1	Fatigue 01/2018
1	Infections 01/2018
1	Neutropenia 01/2018
1	Growth Disorders 12/2017
1	Mastoiditis 10/2017
1	Hepatocellular Carcinoma (Hepatoma) 10/2017
1	GM1 Gangliosidosis (Gangliosidosis GM1) 09/2017
1	Central Nervous System Diseases (CNS Diseases) 11/2016
1	Diabetes Complications 04/2015
1	Glucose Intolerance 04/2015
1	Neoplasms (Cancer) 08/2014
1	Alzheimer Disease (Alzheimer's Disease) 02/2008
1	Neuroblastoma 02/2008

Drug/Important Bio-Agent (IBA)

9	EnzymesIBA 01/2022 - 09/2012
9	Psychosine (Galactosylsphingosine)IBA 01/2022 - 01/2009
8	CholesterolIBA 12/2021 - 11/2014
8	GalactosylceramidaseIBA 01/2021 - 09/2012
6	SphingolipidsIBA 01/2022 - 01/2009
5	LipidsIBA 01/2022 - 01/2018
5	Biomarkers (Surrogate Marker)IBA 12/2020 - 11/2014
3	GlycolipidsIBA 01/2021 - 09/2017
3	CeramidesIBA 01/2020 - 01/2018
2	Hexosaminidase A (Hex A)IBA 01/2022 - 01/2018
2	Pharmaceutical PreparationsIBA 10/2021 - 01/2018
2	Sulfoglycosphingolipids (Sulfatides)IBA 01/2021 - 02/2008
2	Bile Acids and Salts (Bile Acids)IBA 12/2020 - 01/2016
2	CyclodextrinsIBA 10/2019 - 01/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 04/2015
1	CeramidasesIBA 01/2022
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2022
1	Carrier Proteins (Binding Protein)IBA 10/2021
1	GangliosidesIBA 10/2021
1	Galactosylceramides (Galactocerebrosides)IBA 01/2021
1	psychosine-3'-sulfate esterIBA 01/2021
1	N-Acylsphingosine GalactosyltransferaseIBA 01/2021
1	Triglycerides (Triacylglycerol)IBA 01/2020
1	GlycosphingolipidsIBA 01/2020
1	Fenofibrate (CiL)FDA LinkGeneric 01/2020
1	Acid CeramidaseIBA 10/2019
1	GalactosidasesIBA 01/2019
1	HydrolasesIBA 01/2019
1	Lipase (Acid Lipase)FDA Link 01/2019
1	Monomeric GTP-Binding ProteinsIBA 01/2019
1	GTP Phosphohydrolases (GTPases)IBA 01/2019
1	Polytetrafluoroethylene (Teflon)FDA Link 01/2019
1	Basic Helix-Loop-Helix Transcription FactorsIBA 01/2019
1	pazopanib FDA Link 01/2018
1	Cetuximab (Erbitux)FDA Link 01/2018
1	Hexosaminidases (Hexosaminidase)IBA 01/2018
1	Proteins (Proteins, Gene)FDA Link 01/2018
1	SuspensionsIBA 01/2018
1	Angiogenesis InhibitorsIBA 01/2018
1	Tocopherols (Tocopherol)IBA 01/2018
1	Therapeutic UsesIBA 01/2018
1	Choline (Choline Chloride)IBA 12/2017
1	dimemorfan (AT 17)IBA 10/2017
1	Lysergic Acid Diethylamide (LSD)IBA 04/2015
1	Diphtheria ToxinIBA 04/2015
1	IncretinsIBA 04/2015
1	Serine (L-Serine)FDA Link 04/2015
1	liposomal doxorubicin (Doxil)FDA Link 08/2014
1	1-dodecylpyridoxal (PLD)IBA 08/2014
1	temsirolimus FDA Link 08/2014

Therapy/Procedure

5	Therapeutics 01/2021 - 01/2011
3	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2021 - 09/2012
2	Enzyme Replacement Therapy 01/2018 - 09/2012
1	Aftercare (After-Treatment) 01/2022